Definition of do / in phrasal verb from the Oxford Advanced American Dictionary

 

do / in

 phrasal verb
phrasal verb
 
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Phrasal Verbs

    do somebody/yourself in

    (informal)
     
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  1. 1to kill someone/yourself
  2. 2 [usually passive] to make someone very tired The long hike really did me in.
See the Oxford Advanced Learner's Dictionary entry: do / in