Definition of setback noun from the Oxford Advanced American Dictionary

 

setback

 noun
noun
NAmE//ˈsɛtbæk//
 
 
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a difficulty or problem that delays or prevents something, or makes a situation worse The team suffered a major setback when their best player was injured. The breakdown in talks represents a temporary setback in the peace process.
See the Oxford Advanced Learner's Dictionary entry: setback