Definition of Creutzfeldt-Jakob disease noun from the Oxford Advanced Learner's Dictionary


Creutzfeldt-Jakob disease

BrE BrE//ˌkrɔɪtsfelt ˈjækɒb dɪziːz//
; NAmE NAmE//ˌkrɔɪtsfelt ˈjækɔːb dɪziːz//
[uncountable] (abbreviation CJD) Ailments and diseases
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a brain disease that causes gradual loss of control of the mind and body and, finally, death. It is believed to be caused by prions and is linked to BSE in cows. See related entries: Ailments and diseases Word Origin1930s: named after H. G. Creutzfeldt (1885–1964) and A. Jakob (1882–1927), the German neurologists who first described cases of the disease in 1920–1. Creutzfeldt is credited with the first description of the disease in 1920, although the case is atypical by current diagnostic criteria; a year later Jakob described four cases, at least two of whom had clinical features suggestive of CJD as it is currently described.
See the Oxford Advanced American Dictionary entry: Creutzfeldt-Jakob disease