an act of saying or showing that you will not do, give or accept something refusal (of something) the refusal of a request/an invitation/an offer a blunt/flat/curt refusal refusal to do something His refusal to discuss the matter is very annoying. see also first refusalExtra examples He accepted my refusal with a shrug. Her appeals for funds to support the cause were met with blank refusal. If you decide to sell your car, I hope you’ll give me first refusal. a refusal by a patient to accept the recommended treatment a refusal of consent to blood transfusions her utter refusal to do anything to help the enemy’s steadfast refusal to accept defeat the panel’s point-blank refusal to release the information their refusal on religious grounds to perform military service There were a number of reasons given for the refusal of the application. What do you do in the case of a refusal by a patient to accept treatment?