Definition of vicissitude noun from the Oxford Advanced Learner's Dictionary

 

vicissitude

 noun
noun
BrE BrE//vɪˈsɪsɪtjuːd//
 
; NAmE NAmE//vɪˈsɪsɪtuːd//
 
[usually plural](formal)
 
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one of the many changes and problems in a situation or in your life, that you have to deal with the vicissitudes of family life Word Origin early 17th cent. (in the sense ‘alternation’): from French, or from Latin vicissitudo, from vicissim ‘by turns’, from vic- ‘turn, change’.
See the Oxford Advanced American Dictionary entry: vicissitude