American English

Definition of take up with phrasal verb from the Oxford Advanced American Dictionary

 

take up with

 phrasal verb
phrasal verb
 
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Phrasal Verbs

take up with somebody

(informal)
 
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to begin to be friendly with someone, especially someone with a bad reputation

take something up with somebody

 
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to speak or write to someone about something that they may be able to deal with or help you with They decided to take the matter up with their state representative.
See the Oxford Advanced Learner's Dictionary entry: take up with