1 [transitive] screw something + adv./prep. to fasten one thing to another or make something tight with a screw or screws The bookcase is screwed to the wall. You need to screw all the parts together. Now screw down the lid.2 [transitive] to twist something around in order to fasten it in place screw something + adv./prep. She screwed the cap back on the jar. screw something + adj. Screw the bolt tight.