an unreasonable dislike of or preference for a person, group, custom, etc., especially when it is based on their race, religion, sex, etc.a victim of racial prejudiceTheir decision was based on ignorance and prejudice.prejudice against somebody/somethingThere is much less prejudice today against women in the medical profession.prejudice in favor of somebody/somethingI must admit to a prejudice in favor of Ivy League universities.