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Definition of missis noun from the Oxford Advanced Learner's Dictionary

missis

noun
 
/ˈmɪsɪz/
 
/ˈmɪsɪz/
(also missus)
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  1. (informal, becoming old-fashioned) (used after ‘the’, ‘my’, ‘your’, ‘his’) a man’s wife
  2. (slang, becoming old-fashioned) used by some people as a form of address to a woman whose name they do not know

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